Conjunctivitis Morbillivirus Canis Infection Induces Activation of Three Branches of Unfolded Protein Response, MAPK and ApoptosisMorbillivirus canis, commonly named Canine distemper virus (CDV), is a morbillivirus implicated in several signs in the Canidae family. In dogs (Canis lupus familiaris), common signs of infection include conjunctivitis, digital hyperkeratosis and neuropathologies. Even with vaccination, the canine distemper disease persists worldwide so the molecular pathways implicated in the infection processes have been an…viral conjunctivitisJan 08 2025Dermatological manifestations during Dengue, Chikungunya, and Zika infectionsPURPOSE OF REVIEW: Arboviral infections caused by Dengue, Zika, and Chikungunya viruses continue to pose a significant global health threat, particularly in endemic regions. This review is timely because of the increasing prevalence of these infections, driven by factors such as urbanization and climate change. Dermatological manifestations of these viruses are crucial for early diagnosis,…viral conjunctivitisJan 08 2025Molecular characteristics and pathogenicity analysis of infectious laryngotracheitis virus isolated in China from 2015 to 2019The aim of this study was to investigate the molecular characteristics and pathogenicity of recently isolated ILTV strains from China, thereby augmenting our understanding of its prevalence. The complete genome sequences of seven ILTV strains obtained from China between 2015 and 2019 were determined by high-throughput sequencing. Phylogenetic analysis showed that six isolates (SD2015, GD2017,…viral conjunctivitisJan 04 2025Post-translational modifications on protein VII are important during the early stages of adenovirus infectionDue to the importance of post-translational modification (PTM) in cellular function, viruses have evolved to both take advantage of and be susceptible to such modification. Adenovirus encodes a multifunctional protein called protein VII, which is packaged with the viral genome in the core of virions and disrupts host chromatin during infection. Protein VII has several…viral conjunctivitisJan 02 2025Molecular analysis of acute hemorrhagic conjunctivitis in a tertiary care hospital, Kalburgi district, Karnataka 2023CONCLUSION: To summarize, CA24v was identified as an etiological agent responsible for the recent acute hemorrhagic conjunctivitis outbreak in Kalburgi. The CA24v strain detected was closely related to the currently circulating Asian strains.viral conjunctivitisDec 29 2024Possible viral agents to consider in the differential diagnosis of blepharoconjunctivitisCONCLUSION: Prompt recognition of these viral etiologies is essential for appropriate management and prevention of complications. Thus, a thorough understanding of the clinical presentation, epidemiology, and diagnostic modalities is crucial for accurate identification and management of viral blepharoconjunctivitis.viral conjunctivitisDec 26 2024Health-seeking behaviors during an outbreak of acute conjunctivitis in Central IndiaCONCLUSION: Several insights into health-seeking behaviors among individuals with conjunctivitis during an outbreak were identified in this study, which can aid public health interventions during future outbreaks.viral conjunctivitisDec 26 2024Bleb-related endophthalmitis during an epidemic of viral keratoconjunctivitisThere is an annual epidemic of viral conjunctivitis at the onset of the monsoon (rainy) season in North India. This affects a large population, with many patients developing ocular symptoms and then getting better without any treatment as there is no specific therapy for adenoviral infections. However, this creates a dangerous situation for patients with…viral conjunctivitisDec 18 2024 Allergen immunotherapy in Italy: How, when, and why-A real-world study conducted through a patient association CONCLUSIONS: The outcomes of this research pointed out a lot of misinformation surrounding AIT, calling for improvements in awareness and information on its efficacy and safety. Also, we noted a significant reduction in work/school days lost in patients who completed AIT and a good patient-reported safety and efficacy profile. We advocate for better economic accessibility…allergic conjunctivitisJan 15 2025Algorithms in Allergy: Organ-Specific Allergen Challenges for the Phenotyping of Chronic Respiratory DiseasesNo abstractallergic conjunctivitisJan 08 2025Climate change and ocular surface diseasesCONCLUSION: For ocular surface diseases, large epidemiological cohorts have shown climate-related increases in the incidence. A further increase in environmentally associated noxious substances can be expected in the coming decades. In addition to measures to mitigate climate change, the underlying mechanisms of disease development and new approaches to prevention and treatment, such as room humidification,…allergic conjunctivitisJan 08 2025Registries in allergy: Structure, target groups, and key findings of allergy-focused registries in GermanyIn allergology, clinical registries fill knowledge gaps of epidemiology, mechanisms of allergic diseases, and real-world treatment outcomes. Considering the continuous rise of allergic diseases worldwide, registries become increasingly important for the optimization and harmonization of patient care. In the current review, we present four ongoing allergy-focused registries initiated in Germany. We conducted a focused literature…allergic conjunctivitisJan 08 2025Prevalence and demographic profile of keratoconus among high school students in KenyaCONCLUSIONS: Among adolescents, the results of this study indicate a higher prevalence of KC compared to that reported in South Korea, Norway, Brazil and Caucasians in New Zealand, but less than that reported in some countries in the Middle East. Given the high prevalence revealed in this study, a national school screening program and clinical…allergic conjunctivitisJan 08 2025The Role of In Vivo Confocal Microscopy in Ocular AllergiesIn vivo confocal microscopy (IVCM) is a non-invasive imaging technique used to visualize the layers of the cornea and conjunctiva in real time. In patients with atopic keratoconjunctivitis (AKC) and vernal keratoconjunctivitis (VKC), this technology can be useful in diagnosing and monitoring the disease, as well as evaluating the efficacy of treatments. IVCM can reveal…allergic conjunctivitisJan 02 2025The Spectrum of Ocular Diseases in the Onchocerciasis-Endemic Focus of Raga in South SudanCONCLUSION: Despite years of CDTI, the main causes of blindness in Raga County remain onchocerciasis-related blindness observed in 22.6% and cataract observed in 9.3% of the study participants. The study confirmed an epidemiological association between onchocerciasis and epilepsy.allergic conjunctivitisDec 30 2024Allergic rhinitisAllergic rhinitis (AR) is a common disorder that is strongly linked to asthma and conjunctivitis. Classic symptoms include nasal congestion, nasal itch, rhinorrhea and sneezing. A thorough history, physical examination and assessment of allergen sensitization are important for establishing the diagnosis of AR. Intranasal corticosteroids and second-generation antihistamines are the mainstay of treatment. Allergen immunotherapy…allergic conjunctivitisDec 28 2024Risk and protective factors for coronavirus disease 2019 (COVID-19) in allergic rhinitis patients: a national survey in ChinaCONCLUSIONS: This study revealed underlying protective and risk factors, which might be used to improve the management of AR and COVID-19.allergic conjunctivitisDec 25 2024Efficacy of Epinastine Eyelid Cream in Pediatric Vernal Keratoconjunctivitis: A Case ReportAllergic conjunctivitis (AC) is characterized by inflammatory responses in the conjunctiva and is often complicated by atopic dermatitis and mechanical irritation. Vernal keratoconjunctivitis (VKC), a severe subtype of AC, presents unique challenges in its diagnosis and management, particularly in pediatric patients. This case report describes an eight-year-old girl with VKC who exhibited poor adherence to…allergic conjunctivitisDec 24 2024High body mass index with the risk of allergic conjunctivitis in children: a case-control study in Southwest ChinaCONCLUSION: A high BMI (overweight and obesity) can increase the incidence of AC. Breastfeeding and dietary supplementation with fish oil are recommended for children susceptible to AC.allergic conjunctivitisDec 20 2024Postorgasmic illness syndrome benefiting from omalizumab and antidepressant: a case reportCONCLUSION: The patient's symptoms improved significantly with the combination of omalizumab and escitalopram. This case not only provides a new perspective on the management of postorgasmic illness syndrome but also highlights the potential roles of allergic, psychiatric, and endocrinological mechanisms in the etiology and treatment of this complex condition.allergic conjunctivitisDec 20 2024Clinical Trial With a Depigmented, Polymerized Mite Mixture Extract at Maximum ConcentrationsCONCLUSIONS: SCIT treatment of patients with allergic rhinitis or rhinoconjunctivitis and controlled asthma with mixtures of Dpt/Bt and Dpt/Ld allergen extracts at maximum concentrations showed a favourable safety profile.allergic conjunctivitisDec 19 2024 Epidemiology of ophthalmia neonatorum: a systematic review and meta-analysis CONCLUSION: ON is a common ocular morbidity in neonates, especially in those from low-income settings. It is important that all newborns receive adequate preventive care, regardless of their socioeconomic status, in order to reduce the risk of visual impairment and blindness.bacterial conjunctivitisJan 14 2025Distribution and viability of ocular and non-ocular Chlamydia trachomatis in households in a trachoma-endemic community in Oromia, EthiopiaCONCLUSION/SIGNIFICANCE: Using RT-qPCR assay to detect Ct omp2 mRNA to define viability offers a new, informative perspective of trachoma transmission in this community in Ethiopia. The presence of viable Ct on the faces and hands of individuals living in households with people with current ocular Ct infection supports the hypothesis that hands and faces are…bacterial conjunctivitisJan 13 2025A 14-year-old boy with painful oral lesionsThis case concerns a boy presenting with oral pain and multiple mucocutaneous lesions such as mucositis, conjunctivitis, and a rash on the trunk, extremities, and genitalia. The presence of mild respiratory complaints raised suspicion of an extrapulmonary manifestation of Mycoplasma pneumoniae, known as Mycoplasma pneumoniae-induced Rash and Mucositis (MIRM). The patient underwent conservative treatment and…bacterial conjunctivitisJan 13 2025Impact of trachoma elimination efforts in afar regional state, Ethiopia: survey findings from 26 evaluation unitsCONCLUSION: In seven woredas, further rounds of antibiotic mass drug administration are required, complemented by initiatives to promote facial cleanliness and improve environmental conditions. Additionally, surgical campaigns for trachomatous trichiasis (TT) are needed in 12 woredas. There is a critical need to enhance access to improved Water, Sanitation, and Hygiene (WASH) facilities across all surveyed…bacterial conjunctivitisJan 03 2025Variability in the Evaluation and Treatment of Healthy Neonates With Uncomplicated ConjunctivitisCONCLUSIONS: The evaluation and management of neonatal conjunctivitis within United States ambulatory settings are highly variable. Diagnostic studies are underused, resulting in limited etiologic data and a lack of susceptibility-guided treatment. [J Pediatr Ophthalmol Strabismus. 20XX;X(X):XXX-XXX.].bacterial conjunctivitisJan 03 2025Trachoma Impact Survey Results from 31 Woredas in Tigray Region, EthiopiaCONCLUSION: Eight woredas met the criteria to stop MDA for 2 years before the re-survey. However, further rounds of MDA, additional efforts to improve water and sanitation access and ongoing strengthening of surgical services for TT are needed across Tigray.bacterial conjunctivitisDec 27 2024Bleb-related endophthalmitis during an epidemic of viral keratoconjunctivitisThere is an annual epidemic of viral conjunctivitis at the onset of the monsoon (rainy) season in North India. This affects a large population, with many patients developing ocular symptoms and then getting better without any treatment as there is no specific therapy for adenoviral infections. However, this creates a dangerous situation for patients with…bacterial conjunctivitisDec 18 2024
