Cataract Surgery

Double-Masked, Dose-Response, Vehicle-Controlled Study of VVN461 Ophthalmic Solution in Postoperative Ocular Inflammation CONCLUSIONS: In this double-masked, vehicle-controlled study, clinically and statistically significant anti-inflammatory efficacy was seen with few safety issues.

STARGUS: a comparative study of a new swept-source biometer and B-mode ultrasound in dense cataracts CONCLUSIONS: The new SSB Argos^(®), in particular when the ERV mode is used, could be a reliable alternative to B-mode ultrasound for measuring AL in eyes with dense cataracts. It is as effective as ultrasound in measuring the AL, and it could help to improve cataract surgery planning and outcomes.

Quantitative evaluation of inflammation after phacoemulsification surgery: anterior chamber flare and choroidal vascular index CONCLUSION: Particularly in the early period after phacoemulsification, ACF, mCVI and pCVI increased. The increase in ACF lost its significance at the third month and the increase in mCVI and pCVI remained significant, which may indicate that the inflammatory effect of cataract surgery lasts longer in the posterior segment. Total CDE can be used to…

Impact of residual ophthalmic viscosurgical device behind intraocular lens on postoperative intraocular pressure and refractive outcomes in cataract surgery CONCLUSIONS: Residual OVD behind the IOL may elevate IOP and cause refractive changes, emphasizing the need for thorough OVD removal and close postoperative monitoring, especially in patients with thinner lenses.

Novel Subclassification of Presbyopia Based on Lens Functional and Structural Features CONCLUSIONS: We proposed a novel classification of presbyopia using lens functional and structural features.

Incidence of Endophthalmitis after Cataract Surgery in the Setting of Uveitis and/or Immunosuppressive Therapy within the IRIS Registry CONCLUSION: Underlying uveitis diagnosis, systemic corticosteroids and immunosuppressives are associated with an increased likelihood of acute postoperative endophthalmitis following cataract surgery.

Deciphering corneal astigmatism - calculation pitfalls and how to avoid them Options for correcting astigmatism include spectacles or contact lenses, corneal refractive laser surgery or relaxing incisions, toric lenses in the capsular bag, or implantation of supplementary toric lenses in the phakic or pseudophakic eye. This correspondence addresses some of the potential pitfalls which could cause calculation errors when working with astigmatic surfaces and spherocylindrical vergences…

Inappropriate administration of mitomycin in a cataract patient CONCLUSIONS AND IMPORTANCE: This case underscores the significance of system failures in the healthcare environment and how "never events" may occur even with appropriate protocols in place. The improper administration of mitomycin emphasizes the need for enhanced safety measures, including improved medication labeling, consistent use of time-outs, and reinforcing their importance in high-volume environments. System…

Trends in Patient, Surgeon, and Procedural Characteristics of Intraocular Lens Exchange among Medicare Beneficiaries 2011-2020 CONCLUSIONS: The number of IOL exchange procedures performed among Medicare beneficiaries increased over the last decade. Male ophthalmologists in urban locations performed the majority of IOL exchanges. The most common post-operative complication was epiretinal membrane. The rates of corneal decompensation, retinal detachment, and endophthalmitis were low.

Visual Outcomes and Satisfaction in Patients with High Myopia Following Cataract Surgery with Trifocal Intraocular Lens Implantation CONCLUSIONS: Trifocal IOL implantation provides satisfactory full-range visual acuity on the premise of no complications, with a spectacle independence rate of over 90%. Although HOA and trefoil aberration were greater in patients with high myopia, they achieve comparable visual acuity and spectacle independence rates, with a high satisfaction.

Exploring Machine Learning Models for Vault Safety in ICL Implantation: A Comparative Analysis of Regression and Classification Models CONCLUSIONS: Classification models, particularly gradient boosting and random forest, demonstrated strong potential for predicting clinically significant vault categories, enabling personalized surgical planning and improved risk management. While regression models offered moderate insights, their limitations suggest that classification approaches are better suited for clinical applications. Future research should focus on enhancing model accuracy for extreme vault…

Comparison of IOL formula accuracy for eyes with prior scleral buckle surgery CONCLUSIONS: The formulas compared had similar accuracy of the absolute and precision SEQ-PE for eyes with scleral buckles. There was variability in the trueness of the 6 formulas, however. Therefore, surgeons should consider these trends for IOL selection in eyes with scleral buckles.

Efficacy and Safety Evaluation of a New Full Visual Range versus Monofocal IOL in Cataract Patients: A Randomized, Controlled Canadian Clinical Trial CONCLUSION: The FVR group exhibited a continuous range of vision from distance to near. Postoperatively, more than 90% of FVR patients were satisfied with their near vision and had no difficulty doing near vision tasks while being spectacle-free.

Use of Narrow Calibrated Side-Port Technique to Prevent Occurrence of Intraoperative Floppy Iris Syndrome During Phacoemulsification Surgery CONCLUSION: When added to existing surgical techniques, a calibrated side-port incision significantly improves patient outcomes in managing IFIS during phacoemulsification in patients taking alpha-1 antagonist drugs. This modification helps prevent the side-port incision from becoming a focal point for IFIS, thereby enhancing surgical safety and efficacy.

Presumed nonadaptation to a multifocal intraocular lens masking visual loss from a pituitary tumor CONCLUSION: Prior to performing an IOL exchange in patients with persistent visual dissatisfaction after multifocal lens placement, other causes of visual dissatisfaction should be thoroughly investigated.

Refraction Predictability for a Capsulotomy-Fixated Intraocular Lens in Femtosecond Laser-Assisted Cataract SurgeryCONCLUSIONS: Implantation of the capsulotomy-fixated FEMTIS IOL during FLACS is associated with increased systematic refractive PE, which is directly influenced by preoperative anterior chamber depth and lens thickness. IOL constant optimization enhances prediction accuracy. Relevant inaccuracies also persist in modern formulas, indicating that advancements beyond constant optimization might be crucial to enhance the predictability and…

Postoperative Visual Function of Enhanced Monofocal Intraocular Versus Monofocal LensesCONCLUSIONS: The Impress group demonstrated superior intermediate visual acuity and a myopic shift from the target refraction. Preoperative pupil diameter may help identify patients most likely to benefit from the Impress lens. [J Refract Surg. 2025;41(6):e551-e557.].

Risk and Protective Factors for Ocular Surface Disease in Patients with Type 2 Diabetic Mellitus: A Retrospective Cohort StudyPurpose: Identify the risk and protective factors for ocular surface disease (OSD) in patients with type 2 diabetes mellitus (T2DM). Methods: This retrospective cohort study used the Chang Gung Research Database (2005-2020) for patients with T2DM. A total of 161,001 patients were included, of which 915 had OSD and 160,086 did not. The OSD group…

Traumatic Glaucoma Managed With Ab Interno Trabeculotomy (Trabectome®): A Case ReportA 55-year-old patient sustained a bungee cord injury to his left eye, resulting in a traumatic cataract, vitreous prolapse into the anterior chamber, and extensive angle recession. Despite cataract surgery with pars plana vitrectomy and maximal medical therapy, intraocular pressure (IOP) remained elevated at 40 mmHg. The patient was diagnosed with mixed-mechanism traumatic glaucoma. Ab…

Lower Levels of Endogenous Intraocular Interferon Beta in Patients with Primary GlaucomaPurpose: Glaucoma, a neurodegenerative condition of the optic nerve is driven by increased intraocular pressure (IOP) due to fibrotic changes of the trabecular meshwork (TM). Interferon beta (IFN-β), a pleiotropic cytokine is known for its neuroprotective and antifibrotic potential. Hence, we investigated the intraocular status of IFN-β in patients with primary glaucoma. Methods: Aqueous humor…

Oral Antithrombotic Medication Is Associated with Improved Visual Outcomes in Eyes with Submacular Hemorrhage from Wet Age-Related Macular DegenerationCONCLUSIONS: Patients taking oral anticoagulants who then develop an SMH may have better long-term VA outcomes than those who were not. However, this effect was not seen in patients taking oral antiplatelet medications. This suggests that baseline anticoagulants may be associated with improved VA outcomes in eyes that develop an SMH. When controlling for size…

Safety Outcomes Following Implementation of a Systematic Cataract Surgery Protocol at a Tertiary Referral Eye CenterCONCLUSION: Continuous reassessment of standardized protocols for cataract surgery is critical to ensure patient safety.

Toric Intraocular Lens Calculations in Eyes With Corneal EctasiaCONCLUSIONS: The use of multiple measurements, provided by the IK calculator, enhanced astigmatism correction with toric IOLs in eyes with corneal ectasia. The variability in ectatic corneas likely benefits from a multi-measurement approach. [J Refract Surg. 2025;41(6):e558-e568.].

Artificial Intraocular Lenses- the Halcyon Years As Measured by Individual and Corporate Patentable InnovationsCONCLUSIONS: Using patents as a surrogate for creativity in IOL development, the U.S. played a leading role in artificial lens design. Patents for IOLs first increased when the FDA was authorized to classify them as Class III medical devices, while the majority of ownerships shifted from individuals to companies after 1989. The near simultaneous rise…

Chinese expert consensus on the clinical application of presbyopia-correcting intraocular lenses (2025)With the intensification of global population aging, the demand for presbyopia correction continues to rise, and various types of presbyopia-correcting intraocular lenses (IOLs) are being increasingly applied in clinical practice. The experts form the Chinese Cataract and Refractive Surgery Society and Cataract Group of Chinese Ophthalmologist Association, based on the current evidence-based data and through…

Accuracy comparison of intraocular lens power calculation formulas in cataract patients with axial length greater than 28 mm undergoing phacoemulsification with capsular tension ring implantationObjective: To evaluate the accuracy of the Barrett Universal Ⅱ, Haigis, and SRK/T formulas for intraocular lens (IOL) power calculation in cataract patients with axial length >28 mm undergoing phacoemulsification combined with capsular tension ring implantation. Methods: A retrospective case series study was conducted. Data from 26 eyes (26 patients) with cataract (axial length>28 mm),…

Recognition of early cognitive impairment in patients with cataractObjective: To explore the influencing factors of early cognitive impairment in patients with age-related cataract, and to construct a risk prediction model, for the management of patients undergoing day surgery. Methods: This was a cross-sectional study. A total of 137 patients with age-related cataract admitted to the Department of Ophthalmology, Chinese PLA General Hospital from…

Consistency between digital navigation and slit-lamp assisted corneal markingObjective: To investigate the consistency between automatic corneal marking using a surgical navigation system and manual corneal marking assisted by a slit-lamp microscope. Methods: This was a retrospective case series study. Patient data from the Ophthalmology Outpatient Department of Shanghai Sixth People's Hospital, Shanghai Jiao Tong University School of Medicine, from June 2021 to July…

Evaluation of residual internal astigmatism after cataract surgery based on intraocular parameters measured by swept-source OCTObjective: To explore the influencing factors of intraocular residual astigmatism (RIA) after the implantation of non-toric intraocular lens (IOL), and to analyze the differences in the positional characteristics of the IOL and RIA between the eyes. Methods: This was a retrospective case series study. The data of 122 cataract patients (122 eyes, 67 right eyes…

Complications and Management of Cosmetic Iris ImplantsCONCLUSIONS: This case series demonstrates that cosmetic iris implants are associated with serious sight-threatening complications including corneal decompensation, glaucoma, and uveitis. Many patients required multiple surgical interventions after explantation, highlighting the long-term morbidity associated with these devices. The authors recommend that cosmetic iris implantation should be banned worldwide given the substantial risks and lack of…

Spontaneously resolved invasive conjunctival squamous cell carcinoma with anterior chamber invasion in low-grade lymphoma patientCONCLUSIONS AND IMPORTANCE: Invasive conjunctival squamous cell carcinoma is an advanced form of ocular surface neoplasia, typically necessitating extensive surgical excision and chemical or biologic therapy. This case highlights a potential pathway for the spontaneous resolution of squamous cell carcinoma post-incisional biopsy, although the precise underlying mechanisms remain unclear. Understanding these mechanisms could inform future…

Pathophysiology of intraoperative floppy iris syndrome: An unsettled debateIntraoperative floppy iris syndrome (IFIS)--characterized by iris blowing, prolapse, and progressive miosis during phacoemulsification surgery--poses significant challenges for eye surgeons. Despite being described almost 2 decades ago, its pathophysiology remains unclear. Initially, IFIS was thought to be a result of sympathetic signal blockage in the iris dilator muscle, since α-blockers such as tamsulosin were found…

Management outcomes and clinical features of combined exfoliation syndrome with angle closure glaucomaThis study investigated the distinctive features and management outcomes of combined exfoliation syndrome and angle-closure glaucoma (XFS-PACG) through a prospective, multicenter observational cohort study including 350 patients (118 XFS, 127 PACG, 105 combined XFS-PACG). Combined pathology demonstrated unique characteristics including bimodal diurnal IOP fluctuations, asymmetric angle closure correlating with exfoliation material distribution, and accelerated zonular…

Pediatric cataract-part 2 : Surgical treatmentPediatric cataract surgery is very different from adult cataract surgery. A profound understanding of surgical technique, age at time of surgery, combined ocular and systemic diseases to be associated with long-term functional or morphological outcomes is important for planning and performing treatment of cataracts in children. Increased intra- and postoperative risk and individual amblyogenic risk…

Visual outcomes and spectacle independence of a non-diffractive wavefront-shaping intraocular lens in post-LASIK patientsCONCLUSION: In post-LASIK eyes, this wavefront-shaping EROF IOL was well-tolerated and provided an extended range of vision with significantly better UNVA, fewer difficulties in daily activities and higher spectacle independence for near vision compared to normal eyes.

The clinical efficacy of combining endoscopic cyclophotocoagulation (ECP) with cataract extraction in the therapeutic intervention for malignant glaucoma following trabeculectomyCONCLUSIONS: The combination of ECP and cataract extraction proves to be a safe and effective therapeutic approach for managing malignant glaucoma following anti-glaucoma surgery.

The mechanism of promoting angiogenesis after cerebral infarction by scalp acupuncture based on MATN2/WNT3a/β-cateninScalp acupuncture, a therapeutic modality derived from traditional acupuncture theory, has been widely applied in clinical practice for cerebral infarction management in China. In this study, a middle cerebral artery occlusion (MCAO) rat model was established. Therapeutic efficacy was evaluated through multidimensional approaches: (1) Neurological functional assessment using modified Neurological Severity Score (mNSS); (2) Quantitative…

Comparing toric intraocular lens alignment: intraoperative image-guided system versus manual marking in cataract surgery: a randomized clinical trialCONCLUSION: Both the image-guided Callisto Eye system and the manual marking method demonstrated statistically equivalent effectiveness in toric IOL alignment, rotational stability, residual astigmatism, and UDVA.

Optometry co-management of preoperative and postoperative cataract surgery patientsPURPOSE OF REVIEW: As the prevalence of cataracts continues to rise, the increasing demand for cataract surgery may surpass the availability of ophthalmologists. This review examines the role of optometry in the co-management of patients with cataracts, including preoperative and postoperative care, and discusses the implications of expanding optometric scope-of-practice laws.

Incidence and risk factors of rhegmatogenous retinal detachment following paediatric cataract surgery: A systematic review and meta-analysisTo determine the incidence and identify risk factors of rhegmatogenous retinal detachment (RRD) following paediatric cataract surgery. This systematic review and meta-analysis adhered to PRISMA guidelines and was registered in PROSPERO (CRD42024538383). A comprehensive search was conducted across multiple databases, including Cochrane CENTRAL, PubMed/MEDLINE, SCOPUS, Web of Science, ScienceDirect and Google Scholar, up to December…

Inclusion cysts after manual small incision cataract surgery: insights into presentation, management and outcomesWe report a series of three patients who developed conjunctival inclusion cysts following manual small incision cataract surgery (MSICS). Presenting symptoms included foreign body sensation and ocular irritation, sometimes mistaken for filtering blebs. Diagnosis was confirmed through slit-lamp examination, ultrasound biomicroscopy (UBM) and anterior segment optical coherence tomography (AS-OCT). Surgical management varied: two cases underwent…

Current practice patterns in biometry and intraocular lens calculation in SpainPURPOSE: To describe the current available technical resources, preferences and common practices in biometry and intraocular lens (IOL) calculation in Spain.

Analysis of sustainability strategies in cataract surgery and surgeon perspective in reducing carbon footprintCONCLUSION: This review provides evidence that sustainable practices in cataract surgery can be successfully implemented while maintaining clinical safety. The development of research and practices in this field is critically important for establishing more environmentally responsible healthcare systems for future generations. Widespread adoption of sustainable cataract surgery practices is essential for reducing environmental impacts and…

Lens position change following cataract surgery in eyes with thick lenses: an SS-OCT based studyCONCLUSION: Postoperative forward IOL movement contributes to myopic PEs of eyes with thick lenses.

Postural stability and optic flow sensitivity following sight restoration from congenital bilateral cataractsVision is crucial for maintaining balance and facilitating locomotion. Optic flow, for example, provides key self-motion cues for navigation. Congenital blindness typically leads to increased postural sway and impaired navigation. Here, we investigated postural stability and optic flow sensitivity in individuals surgically treated for congenital dense bilateral cataracts years after birth. Experiment 1 assessed whether…

An applied study of phacoemulsification cataract surgery with the mortise and tenon limbal incisionThis retrospective study aims to evaluate the design, intraoperative stability, and postoperative anterior chamber sealing efficacy of mortise and tenon limbal incisions (MTLIs) compared to clear corneal incisions (CCIs) in phacoemulsification cataract surgery, focusing on its safety and effectiveness. 564 patients (MTLI = 282, CCI = 282) undergoing phacoemulsification were stratified by Emery-Little nuclear grades…

Artificial intelligence in ophthalmology: opportunities, challenges, and ethical considerationsCONCLUSIONS: AI is rapidly transforming vision sciences by improving diagnostic accuracy, streamlining clinical workflow, and broadening access to quality eye care, particularly in underserved regions. Its integration into ophthalmology and optometry thus holds significant promise for enhancing patient outcomes and optimizing healthcare delivery. However, to harness the transformative potential of AI fully, sustained multidisciplinary collaboration,…

Reproducibility and accuracy of corneal curvature measurements in patients with and without dry eye: a device-based studyCONCLUSION: Dry eye significantly affects the reliability of corneal curvature measurements, especially with optical reflection-based devices. Corneal topography and Pentacam are more sensitive to tear film abnormalities, while the IOL Master 700 and OPD-Scan III show more consistent results, making them preferable for clinical practice, such as clinical applications including refractive surgery planning, contact lens…

Clinical Outcomes and in vivo Aberrometry Following the Implantation of a Monofocal IOL with Positive AsphericityCONCLUSION: In vivo wavefront analysis of eyes implanted with this enhanced monofocal IOL suggests that the IOL's positive asphericity profile incremented the pre-existing corneal aberrations, leading to useful intermediate and near vision while maintaining distance-corrected visual acuity better than 20/25 in all eyes.

Endophthalmitis After Retinal Surgery: A 8-Year Medicare AnalysisCONCLUSION: The overall endophthalmitis rate following retina surgery was 0.28%. Patient age, CCI and PPV indication (complex RD and macular surgery vs. standard RD) were associated with increased endophthalmitis risk. No associations were identified between any surgeon characteristics and postoperative endophthalmitis risk.

Fluocinolone acetonide (FAc) implant in the treatment of retinal angiopathy macular edema in ATTR V30M patientsCONCLUSIONS: patients with macular edema due to RAA treated with the FAc implant showed sustained increased functional results and anatomical improvement compared to baseline.

Potential relationship between cataract surgery and ocular Demodex colonizationCONCLUSION: Our study revealed a significant increase in Demodex spp. prevalence at the first postoperative month in patients who underwent uncomplicated cataract surgery and who did not have preoperative dry eye syndrome or ocular surface disease. In light of our findings, ocular surface symptoms, such as stinging, burning, tearing, and itching, following cataract surgery should…

Long-term refractive changes after pediatric cataract surgery: an average follow-up of 15 yearsCONCLUSIONS: Refractive changes following pediatric cataract surgery were greater in eyes that underwent surgery at a younger age. In cases operated on at or before 2 years of age, median myopic shifts (in bilateral cases) or anisometropic changes (in unilateral cases) ranged from -8 to -11 D in both aphakic and pseudophakic groups over an…

Comments on: A study on the association of A-scan parameters and intraoperative complications during cataract surgery in eyes with pseudoexfoliation syndromeNo abstract

Authors response to comment on "A study on the association of A-scan parameters and intraoperative complications during cataract surgery in eyes with pseudoexfoliation syndrome"No abstract

Lens parameters and myopic shift in nuclear cataract after vitrectomyCONCLUSIONS: Changes in lens refractive index are the main cause of lenticular myopia induced by nuclear cataract after PPV. Lens density can be used to assess the change of lens refractive index and lens power in vivo.

Cataract surgical training in Poland: analysis of the European board of ophthalmology survey resultsBACKGROUNDS/OBJECTIVES: This study, part of a series, aims to present and analyze the results of the Polish cohort in a European Board of Ophthalmology (EBO) survey on cataract surgical (CS) training in Europe, highlighting national traits and contributing to the discussion on standardizing ophthalmology training.

Evaluation of dry eye pre and post phacoemulsification in diabetic patientsCONCLUSION: Three months after cataract surgery, significant improvements in OSDI scores, TBUT, and Schirmer's test values were observed, indicating a recovery in dry eye status. Diabetic patients experienced more pronounced early postoperative changes but demonstrated comparable recovery trends to non-diabetics by three months. These findings highlight the importance of monitoring dry eye parameters in diabetics,…

Deep Fungal Stromal Keratitis After Cataract Surgery: A Case ReportFungal keratitis is a vision-threatening infection that typically originates at the ocular surface and gradually invades the deeper layers of the cornea. We report a rare fungal keratitis confined to the deep stromal layer that developed following cataract surgery. An 81-year-old woman presented with a creeping white opacity on the posterior corneal surface in the…

Multicenter Retrospective Study of Spiroplasma ixodetis Infantile Cataract in 8 Countries in EuropeSpiroplasma ixodetis has been reported to cause the rare combination of cataract and uveitis in infants. Through a retrospective analysis of available literature and additional unpublished cases, we identified 28 eyes from 18 infants from 8 countries in Europe with cataracts and intraocular inflammation. The cataracts were bilateral in 55.6%, unilateral in 44.4%, and progressive…

Differences in Aqueous Humor Cytokine Concentrations According to the Presence of Posterior Subcapsular Cataract: A Prospective Case-Control StudyCONCLUSION: IFN-γ expression tended to be higher in eyes with PSC than in those without PSC, suggesting a possible role in PSC pathophysiology.

Surgical Outcomes of Gonioscopy-Assisted Transluminal Trabeculotomy (GATT) in Primary and Secondary Open- and Closed-Angle GlaucomaBackground: Gonioscopy-assisted transluminal trabeculotomy (GATT) is a minimally invasive, ab interno conjunctival-sparing glaucoma surgery aimed at the trabecular meshwork and the inner wall of Schlemm's canal. The goal of this study is to report on the success of GATT in a large group of patients with a wide variety of open- and closed-angle glaucomas with…

Predictive Value of Optical Coherence Tomography Biomarkers in Patients with Persistent Diabetic Macular Edema Undergoing Cataract Surgery Combined with a Dexamethasone Intravitreal ImplantBackground: Diabetic macular edema (DME) is the most common cause of vision loss among diabetic patients. The first-line treatments for DME are anti-vascular endothelial growth factor (VEGF)-drugs, while intravitreal steroids are generally reserved for second-line treatment. Limited data exist on the role of optical coherence tomography (OCT) biomarkers as predictors of success in non-responders to…

Affordable Sinskey Hook Goniotomy and Cataract Surgery in Black and Afro-Latino Patients Diagnosed with Glaucoma: Retrospective Real-World One-Year ResultsBackground/Objectives: This study aimed to evaluate the effectiveness of early phacoemulsification cataract surgery combined with goniotomy using a Sinskey hook in patients with glaucoma. Methods: This was a retrospective study conducted at Advanced Eye Care of New York; a private practice located in New York City. Most patients carried diagnoses of mild to moderate glaucoma…

Rho-Kinase Inhibitors in the Management of Fuchs Endothelial Corneal Dystrophy: A ReviewFuchs endothelial corneal dystrophy (FECD) is the most common corneal endothelial dystrophy. It is characterized by the progressive loss of corneal endothelial cells (CECs), guttae formation on the Descemet membrane, and corneal edema, leading to visual impairment. Corneal transplantation remains the standard treatment, but it has limitations such as donor shortages, infection risk, and graft…

Long-Term Clinical and Structural Outcomes Following Iris-Claw IOL Exchange for Dislocated Intraocular LensesObjectives: Intraocular lens dislocation is a well-recognized complication of cataract surgery, necessitating secondary interventions such as retropupillary iris-claw IOL implantation. While effective, this procedure requires larger incisions that may induce significant astigmatism. This study aimed to (1) evaluate anterior chamber changes following retropupillary ICIOL implantation and (2) compare surgically induced astigmatism between corneal and scleral…

Paediatric glaucoma in Stickler syndromes: a comprehensive review of prevalence, comorbidities and outcomesCONCLUSIONS: Early identification of clinical signs is critical for effective intervention. Paediatric patients with Stickler syndrome, particularly those with cataract or hearing loss, are at higher risk of glaucoma and, therefore, should be closely monitored, in addition to regular retinal assessments. Given the limitations of this review-including small sample sizes and variable diagnostic methods-larger standardised…

Impact of Well-Controlled Type 2 Diabetes on Corneal Endothelium Following Cataract Surgery: A Prospective Longitudinal AnalysisBackground: The aim of this study was to evaluate corneal endothelial changes following phacoemulsification cataract surgery with intraocular lens implantation in patients with type 2 diabetes (study group) and without diabetes (control group). The study aimed to determine the extent of endothelial cell damage and the regenerative capacity of the cornea in patients with well-controlled…

Visual field outcomes after cataract surgery with or without microinvasive glaucoma surgery in open-angle glaucoma: a systematic review and meta-analysis of RCTs reporting visual field resultsCONCLUSION: Among the MIGS devices studied (iStent and Hydrus), combining them with cataract surgery provided VF benefits in terms of rate of deterioration and decline, and reduced medication dependence. Standardised follow-up and reporting practices are essential for evaluating MIGS's role in glaucoma management.

Bilateral Choroidal Detachment Following Pseudophakic Cystoid Macular Edema Treatment with Oral AcetazolamideCONCLUSIONS: Carbonic anhydrase inhibitors (CAIs) such as acetazolamide, although commonly used to manage intraocular pressure, can cause choroidal effusion-a rare but potentially sight-threatening complication. Ophthalmologists should exercise caution, particularly in elderly patients, and be alert to early signs of this adverse effect. Early diagnosis and prompt management are essential to prevent permanent visual damage. To…

Vector analysis valuation of astigmatism in the cornea after femtosecond laser-assisted corneal astigmatism incision in cataract surgeryCONCLUSION: This study demonstrated that femtosecond laser-assisted anterior corneal penetrating arc incision safely and effectively reduced corneal astigmatism after cataract surgery; however, there was an overall under-correction. By conducting a long-term analysis of the APAK results, further studies can help optimize nomogram parameters to improve the precision of femtosecond laser-assisted astigmatism keratotomy cylindrical error correction.

Ex Vivo Microsuturing of the Human Anterior Lens Capsule Using 10-0 Sutures: A Technical Feasibility ReportThe human lens capsule is a robust, transparent basement membrane commonly discarded during cataract surgery. Although its use as a biological graft has gained interest in ocular surgery, practical methods for securing the capsule, such as suturing, have not been evaluated. This technical report presents the first in vitro assessment of anterior lens capsule sutureability…

Preferred practice patterns of endophthalmitis management and prevention: A survey among the members of Vitreoretinal Society of India - Study by the VRSI study groupCONCLUSION: Majority of the Indian vitreoretinal surgeons felt the need for amendment in the EVS guidelines, but would prefer to follow the EVS guidelines for managing endophthalmitis at present.

The Association Between Sleep Health and a History of Cataract Surgery in the United States Based on the National Health and Nutrition Examination Survey (NHANES) 2005-2008Background: The aim of this study was to assess the relationship between sleep-related variables (sleep duration, sleep trouble, and sleep disorder), comprehensive sleep patterns, and the reported history of cataract surgery in the U.S. population aged 20 years and older. Methods: We utilized data from the National Health and Nutrition Examination Survey (NHANES) 2005-2008 database.…

Evaluating the access and utilization of eyecare services after the adoption of eyecare PBF and its financial sustainability: the case of RwandaCONCLUSION: The study reveals contributions of eye PBF to the eye care performance as well as health system challenges, including financial sustainability issues, that calls for policy makers and development partners to act.

Impact of Best Corrected Final Visual Acuity on the Performance of Intraocular Lens Power CalculationsCONCLUSION: Better IOL power predictions were noted by limiting the study to eyes with BCFVA of 0.20 LogMAR or better.

Clinical feasibility of the ESCRS IOL power calculatorCONCLUSIONS: The ESCRS calculator allows efficient and up-to-date IOL calculations in routine clinical practice. The predictive accuracy of the ESCRS calculator is superior compared with older biometric formulas.

Comparison of Conventional Keratometry and Total Keratometry in Untreated Myopic Eyes and Eyes After Keratorefractive Lenticule Extraction (KLEx)CONCLUSION: This study demonstrates that TK-values provide a more comprehensive assessment of corneal power, especially after KLEx, where changes in the posterior corneal surface become increasingly significant. The correlations suggest that patients with higher degrees of preexistent myopia or significant amount of laser ablation require special consideration in their refractive corneal assessments.

Corneal Endothelial Changes After Phacoemulsification Using the Eight-Chop Technique in Diabetic EyesBackground/Objectives: To analyze corneal endothelial changes and intraocular pressure (IOP) after phacoemulsification combined with the eight-chop technique and intraoperative parameters in patients with diabetes mellitus. Methods: The eyes of patients with cataracts who underwent phacoemulsification were analyzed in this study. Based on their hemoglobin A1c levels, patients were divided into two groups. The eight-chop technique…

Quality and Readability of Patient Educational Materials Generated by ChatGPT-4o for Pediatric Ophthalmologic SurgeriesCONCLUSIONS: ChatGPT-4o-generated PEMs on pediatric ophthalmologic surgical conditions are currently inferior in quality to PEMs on the AAPOS website. However, because ChatGPT is continually being updated and trained, this study should be repeated in the future to determine whether metrics improve over time. [J Pediatr Ophthalmol Strabismus. 20XX;X(X):XXX-XXX.].

The Role of IDO Activity in Cataract Progression: Correlation to Age and Cataract SeverityCONCLUSION: Patients with SPONCS 2 cataract exhibit increased susceptibility to elevated IDO activity and heightened kynurenine production. IDO serves as a more reliable prognostic marker for cataract progression than chronological age. Furthermore, IDO activity may be associated with reduced glutathione levels in human lens epithelial cells, suggesting a potential link between the enzyme and oxidative…

Application of generative adversarial networks in the restoration of blurred optical coherence tomography images caused by optical media opacity in eyesCONCLUSIONS: GANs can be used to restore blurred OCT images caused by optical media opacity in eyes. Future studies are warranted to optimise this technique before the application in clinical practice.

Corneoscleral plaque brachytherapy using 'BARC I-125 Ocu-Prosta seeds' in the management of iridociliary melanomaWe present the case of a woman in her late 40s who presented with an iris lesion extending to the ciliary body and mature white cataract with a visual acuity of perception of light in her right eye. The tumour was managed with Bhabha Atomic Research Centre Iodine-125 (BARC I-125) Ocu-Prosta seeds plaque therapy with…

Descemet membrane endothelial keratoplasty after cataract surgery with presbyopia-correcting intraocular lens for coexisting Fuchs endothelial corneal dystrophy and cataractCONCLUSION: DMEK staged after implantation of presbyopia-correcting IOLs is a viable option for patients with coexisting FECD and cataract.

Visual performance during night driving after intraocular refractive surgery proceduresINTRODUCTION: Cataracts reduce visual acuity and contrast sensitivity, and increase photic phenomena, especially at night. Recent advancements in cataract surgery have improved intraocular lens (IOL) designs. Monofocal, multifocal, and extended depth-of-focus IOLs offer different vision ranges but can still cause adverse visual effects like reduced contrast sensitivity and photic phenomena, affecting night driving. Investigating how…

Primary Vitreoretinal Lymphomas: A Diagnostic Challenge - Report of Two Recent Cases with Retinal Biopsies and Molecular Investigations in Halifax, Nova ScotiaCONCLUSION: PVRLs are rare, and establishing the diagnosis is difficult. The traditional use of vitreous cytology has its limitations. Recent molecular advances, in particular the detection of MYD88 mutation, are extremely helpful in confirming the diagnosis, but in certain cases, retinal biopsies may still be required.

Surgical Safety Checklist in ophthalmology: Proposal for a tertiary hospitalAdverse events due to unsafe healthcare practices constitute a serious global problem. The World Health Organization (WHO) has recognized healthcare insecurity as a public health issue and has undertaken various initiatives to safeguard patient safety. The Surgical Safety Checklist (SSC) is one of the tools implemented that has proven to be most effective in in…

The Utility of Virtual Reality in Ophthalmology: A ReviewVirtual reality (VR) has been implemented in multiple facets of healthcare and the study of medicine. In the field of ophthalmology, VR facilitates surgical and non-surgical training while assisting in diagnosis and treatment. Our goal was to explore the applications and feasibility of VR in ophthalmology. We performed a search of the literature on the…

TRPV1 Attenuates Epithelial-Mesenchymal Transition via Calpain-Protein Tyrosine Phosphatase Pathway in Lens Epithelial CellsTRPV1, which is widely expressed throughout the body, is a non-selective cation channel activated by capsaicin. We previously reported that TRPV1 activation suppressed TGFβ2-induced epithelial-mesenchymal transition (EMT) by inhibiting Epidermal Growth Factor Receptor (EGFR) phosphorylation in lens epithelial cells (Sugiyama et al., 2021). However, the detailed molecular mechanism remains unclear. In this study, we focused…

Comparative study of efficacy and safety of pulse versus half-pulse steroid therapy for Vogt-Koyanagi-Harada DiseaseCONCLUSIONS: No significant difference in clinical efficacy for VKH disease was observed between conventional steroid pulse therapy and half-pulse therapy, and by reducing the total steroid dose, half-pulse therapy potentially lowers the risk of adverse effects related corticosteroid.

Posterior Polar Cataracts: A Comprehensive Review of Management StrategiesCONCLUSION: This mini-review serves as a comprehensive guide for both trainee and practicing ophthalmologists alike, updating them on recent advances in posterior polar cataracts. It also highlights the inherent challenges and key considerations that clinicians must carefully navigate in this evolving field.

Pooled Analysis of Three MicroShunt Studies in Primary Open-Angle Glaucoma Evaluating Different Concentrations of Applied Mitomycin CCONCLUSIONS: IOP and glaucoma medication use at year 2 were lower, and complete success rate was higher, in patients administered 0.4 mg/ml than 0.2 mg/ml MMC. Although there is no consensus on the optimal concentration of MMC, these findings may guide surgeons until further evidence from controlled trials becomes available.

Outcomes of Phacogoniotomy for Medically-Controlled and Uncontrolled Primary Open-Angle Glaucoma with Cataract: A Multicenter StudyCONCLUSION: POAG with cataract could be effectively treated by phacogoniotomy, regardless of medically-controlled or medically-uncontrolled status at baseline.

Risk factors for error in refractive astigmatism after toric intraocular lens implantation in Chinese patientsCONCLUSIONS: Factors contributing to ERA after toric IOL implantation include age, AL and ACD change before and after the surgery.

Posterior optic capture for repositioning of dislocated three-piece intraocular lens: a single center retrospective studyCONCLUSIONS: POC is a minimally invasive and straightforward technique for intermediate-term fixation of dislocated three-piece IOLs.

Persistent Anterior Uveitis Following Cataract SurgeryCONCLUSIONS: In this study, 1.1% of eyes developed persistent anterior uveitis following cataract surgery. Younger age, Black race, and wet age-related macular degeneration should be investigated as potential risk factors to improve its prophylaxis, identification, and management.

Nystagmus in Clinical Practice: From Diagnosis to Treatment-A Comprehensive ReviewNystagmus, a common yet intricate ocular movement disorder, significantly contributes to visual morbidity in the paediatric and adult populations. Defined by involuntary, rhythmic, to-and-fro eye movements, this condition may manifest as an isolated anomaly or harbour more serious ocular or systemic pathologies. Its presence often provides vital diagnostic clues, emphasizing the importance of thorough evaluation…

Evaluating the generalizability of video-based assessment of intraoperative surgical skill in capsulorhexisCONCLUSION: Model performance improved with the domain adaptation methods we evaluated, but it fell short of within-dataset performance. Our results provide benchmarks on a public dataset for others to compare their methods.

Normative Values on Stromal Curvature, Power and Corneal-Stromal Curvature Ratios From a Hybrid AS-OCTCONCLUSION: This study provides the first normative values for stromal curvature and its ratios with anterior and posterior curvature. These findings may have implications for corneal- and lens-based surgeries and diagnostics.

A New Vision for Site-Neutral PolicyNo abstract

Metabolomic Profiling of Ocular Fluid Identifies Host Response Factors for Risk Stratification in Bacterial EndophthalmitisCONCLUSIONS: This report is the first of a set of metabolite biomarkers in ocular fluid that correlate with the severity of bacterial endophthalmitis. These biomarkers have the potential to aid in risk stratification and personalized treatment approaches. The metabolomic profiles generated in this study provide insight into the host response mechanisms and the pathophysiology of…

Objective Quality Assessment of the Capsulorhexis - A Novel Augmented Reality Tool for Trainees and ExpertsCONCLUSION: Augmented reality can assist in cataract training. The Custom Surgical MicroREC system can have a positive influence on capsulorhexis quality in a training environment. Automated quality metrics measured by the augmented reality software provide an objective quality score of the performed surgical procedure. As the tested augmented reality system can be used in training…

Masquerade Syndrome Revealing a Vitreous Metastasis from Adenosquamous Lung Carcinoma in a Patient Treated with PembrolizumabCONCLUSION: Masquerade syndrome uveitis can may delay diagnosis and worsen outcomes. In case of failure of anti-inflammatory treatment, a cytological analysis should be conducted to confirm a tumoral origin.

Management of endophthalmitis: to culture or not to culture?PURPOSE: To review the role of microbial cultures in managing endophthalmitis following cataract surgery and intravitreal injections.

Rotational stability, centration, and patient satisfaction with the Clareon Panoptix Toric intraocular lensCONCLUSION: The bilateral implantation of the Clareon PanOptix Toric IOL demonstrates excellent rotational stability, minimal decentration, and effective astigmatism correction. It provides strong visual acuity outcomes and high patient satisfaction, making it a viable option for patients seeking spectacle independence.

Effectiveness of the Better Operative Software Outcomes Tool for Monitoring Cataract Surgery Outcomes in Inhambane Province, Mozambique: Prospective Pilot Diagnostic Accuracy StudyCONCLUSIONS: The BOOST Cataract app is a valuable tool for assessing suboptimal cataract surgery outcomes without waiting for the completion of postoperative treatment in settings where postoperative follow-up is incomplete. In resource-limited eye care systems, the BOOST Cataract app provides an opportunity to assess outcomes and analyze results to develop specific strategies to improve quality…

Depicting the Epithelium and Stroma Profiles of Post-Laser Vision Correction Ectasia by Optical Coherence TomographyCONCLUSIONS: The characteristic remodeling pattern and the machine-derived SD-OCT parameters describing the epithelium remodeling of post-LVC ectasia could potentially be used for its diagnosis.

The Effects of Stress Ball Practice on Patient Anxiety, Pain and Vital Signs During Cataract Surgery: A Randomized Controlled TrialCONCLUSION: The results of this study demonstrated that using a stress ball during cataract surgery decreased pain and anxiety levels in patients but also improved vital signs; however, it had no effect on oxygen saturation.

Phase recognition in manual Small-Incision cataract surgery with MS-TCN + + on the novel SICS-105 datasetManual Small-Incision Cataract Surgery (SICS) is a prevalent technique in low- and middle-income countries (LMICs) but understudied with respect to computer assisted surgery. This prospective cross-sectional study introduces the first SICS video dataset, evaluates effectiveness of phase recognition through deep learning (DL) using the MS-TCN + + architecture, and compares its results with the well-studied…

Evaluation of Turkish Ophthalmologists' Opinions on Surgical Waste During Cataract SurgeryPurpose: Objective: We aimed to investigate the attitudes of ophthalmologists toward the excessive amount of waste generated during modern cataract surgery practices. Methods: Survey study and a prospective, cross-sectional, descriptive study. An online questionnaire consisting of 23 questions was directed to ophthalmologists practicing in Erzurum Province and its surroundings. Duplicate responses were prevented by allowing…

Ocular Mucous Membrane Pemphigoid: Immunomodulation in a Patient with Human Immunodeficiency Virus InfectionCONCLUSION: Systemic immunosuppression is essential in patients with oMMP to prevent disease progression. It can be safely instituted in patients with HIV infection via a multi-disciplinary approach with stringent monitoring of systemic parameters and CD4 counts.

Predictive Factors for Ocular Hypertension and Glaucoma Secondary to Uveitis: Insights from a Tertiary Referral HospitalCONCLUSION: UG/OHT-SU is a specific condition that affects a notable proportion of uveitis patients in Turkey, requiring a multidisciplinary approach. In patients with uveitis, elevated peak IOP, pronounced anterior chamber reaction and synechia formation are crucial factors in the progression to glaucoma and the escalating necessity for surgical intervention. Early and effective control of inflammation…

Intraoperative optical coherence tomography in glaucoma surgery with Ex-PRESS() implantIntroductionTo present the correct placement of the Ex-PRESS^(®) implant in the anterior chamber with the intraoperative optical coherence tomography (i-OCT) scan. To the best of our knowledge, this is the first publication to report the use of i-OCT during an Ex-PRESS^(®) glaucoma implant procedure.Case reportWe report the case of a phakic, 48 year-old South American…

SASVi: segment any surgical videoCONCLUSION: SASVi can serve as a new baseline for smooth and temporally consistent segmentation of surgical videos with scarcely available annotation data. Our method allows us to leverage scarce annotations and obtain complete annotations for full videos of the large-scale counterpart datasets. We make those annotations publicly available, providing extensive annotation data for the future…

An improved technique to treat persistent extensive Descemet's membrane detachment following cataract surgery: a case reportNo abstract

Patientenberichtete Ergebnisse von retrobulbärer versus topischer AnästhesieCONCLUSION: Our results indicate that patients receiving RBA have significantly less pain intraoperatively than those with TA and TAG. The addition of an anesthetic gel to TA showed a slight, but not significant, reduction in pain. Zielsetzung: Das Ziel dieser prospektiven klinischen, monozentrischen Beobachtungsstudie war, die Schmerzempfindung von Patient*innen während einer Kataraktoperation zu erfassen.

Timing of Epiretinal Membrane Surgery After Uncomplicated Retinal Detachment RepairPurpose: To evaluate the features and outcomes of postoperative epiretinal membranes (ERMs) after retinal detachment (RD) repair based on the timing of macular peeling (MP). Methods: This retrospective consecutive case series comprised patients who had rhegmatogenous RD repair, developed an ERM, and had MP within 1 year. Results: Of the ERMs, 91% (50/55) were diagnosed…

Updated study on demographic and ocular biometric characteristics of cataract patients indicates new trends in cataract surgeryTo assess changes in the demographics and ocular biometric characteristics of cataract patients over the past decade to identify trends that may impact cataract surgery as well as design and selection of intraocular lenses. Retrospective study. Clinicodemographic and ocular biometric data from swept-source optical coherence tomography were retrospectively analyzed for 25,192 eyes of 25,192 patients…

CatSkill: Artificial Intelligence-Based Metrics for the Assessment of Surgical Skill Level from Intraoperative Cataract Surgery Video RecordingsCONCLUSIONS: The proposed AI-derived CSAMs provide a high level of reliability in assessing the ability of surgeons to maintain eye neutrality, centration, and focus level during cataract surgery. Furthermore, downstream analysis using an ML model for surgical-level classification indicates that the proposed CSAMs provide significant predictive value for assessing the overall training level of the…

Neurosensory binocular vision after bilateral implantation of an extended depth of focus intraocular lens with micro-monovision: a prospective cohort studyCONCLUSION: Bilateral EDOF IOL implantation with micro-monovision successfully treated cataract, provided reliable binocular far and intermediate visual acuity, good neurosensory binocular vision and patient satisfaction. It achieved better far stereoscopic vision than multifocal IOLs, but lagged behind in near visual acuity, near spectacle independence and binocular contrast sensitivity.

Efficacy, safety, and satisfaction in patients with a functional 5-focus pseudophakic lens 2 years after surgeryCONCLUSION: Patients underwent safe bilateral implantation with Intensity SL IOL, achieving spectacle independence in most cases, and reported a high degree of satisfaction, refraction, and vision stability 24 months after surgery.

Retrospective evaluation of changes in choroidal thickness after cataract surgeryIn this retrospective study, we investigated the changes in choroidal thickness (CT) using enhanced depth imaging spectral domain-optical coherence tomography (EDI-OCT) and intraocular pressure (IOP) following phacoemulsification. Twenty eyes of 18 patients who underwent phacoemulsification and intraocular lens implantation were included in this study. All patients underwent a detailed ophthalmologic examination. EDI-OCT was used to…

A Questionnaire Study on Patient Perspectives of Sedation for Ophthalmic ProceduresIntroduction Ophthalmic procedures, such as cataract and refractive surgery, are prevalent in the United States and are often associated with significant preoperative anxiety among patients, which can impact patient comfort and surgical outcomes. Sedation is used in the vast majority of these procedures to reduce anxiety and improve patient cooperation. However, there is limited information…

Postoperative amblyopia in children with congenital cataracts: a systematic review and meta-analysisThis systematic review and meta-analysis aimed to estimate the prevalence of amblyopia following congenital cataract surgery in children and evaluate key prognostic factors, including age at intervention, cataract phenotype, and follow-up duration. We systematically searched PubMed, EMBASE, and the Cochrane Library for studies published between January 1, 1981, and March 1, 2023. We included clinical…

Timing of the modified yamane technique in complicated cataract surgery: same session or second session?CONCLUSION: In cases of complicated cataract with loss of capsular support,the MYT,whether performed in the same session or in a second session, yielded comparable visual and refractive outcomes. While complications were more frequent in the early postoperative period in the group undergoing surgery in the same session,no complications were observed in either group during the…

Iris retractor-assisted cataract surgery with modified scleral fixation for treating subluxated lensesCONCLUSION: This modified technique simplifies the surgical procedures for treating severe lens subluxation and reduces postoperative complications.

Visual outcomes of aberration neutral versus monofocal plus IOLs in triple DMEK surgeryCONCLUSION: Both IOLs can provide favorable corrected and uncorrected VA in triple DMEK eyes. Eyhance may provide better DCIVA(Uni) and UIVA(Uni) in single eyes and better DCNVA(Uni/Bi) in all eyes up to six months postoperatively.

Cost analysis of immediate versus delayed bilateral cataract surgery in seniors in community-based ambulatory surgical centers in a post-COVID-19 eraCONCLUSIONS: The average costs of cataract extraction among senior patients in ambulatory surgical centers were significantly lower for ISBCS compared to DSBCS.

Intracameral medications in cataract surgeryCONCLUSION: Intracameral drug administration is a valuable adjunct in cataract surgery, enabling surgeons to manage routine and complex cases more effectively. Understanding their appropriate use and potential risks is essential to maximize patient safety and surgical success.

Comparison of 11 intraocular lens power calculation formulas in eyes undergoing simultaneous cataract surgery and Descemet membrane endothelial keratoplastyCONCLUSION: Prediction of the postoperative refraction in eyes requiring cataract surgery and DMEK is still challenging and not as accurate, as in healthy eyes without corneal abnormalities. In our case series, the Barrett Universal II formula achieved the overall best results. Although not being statistically significant, this outcome should be taken into account, when calculating…

Efficacy of topical cyclosporine A in optimizing ocular surface and relieving dry eye symptoms after cataract surgery: a systematic review and meta-analysis of randomized controlled trialsCONCLUSION: Topical CsA significantly improves ocular surface and tear film parameters following cataract surgery and may be considered for the postoperative management of ocular surface disturbance and dry eye. However, considering the very low to moderate certainty of evidence, further high-quality RCTs are needed to validate for these findings.

Clinical Management of Vision Degrading Myodesopsia from Vitreous Floaters - Observation vs. Limited Refractive VitrectomyCONCLUSIONS: Patients with vision degrading myodesopsia from vitreous floaters can be managed by observation or vitrectomy. Objective quantitative measures of vitreous echodensity and contrast sensitivity aid patient selection for observation. These patients were younger and phakic, had floaters from myopic vitreopathy without PVD, and had less vitreous echodensity, as well as better contrast sensitivity.

Ultrasonographic Appearance of a Posterior Lenticonus in a CatThe objective of this study is to present high-quality and up-to-date ocular ultrasonographic images and videos of a posterior lenticonus with concomitant mature cataract in a cat. Additionally, the clinical findings, surgical treatment, and outcome are reported for completeness and to confirm the diagnosis. An 8-year-old castrated male domestic shorthair cat presented due to unilateral…

Assessing the clinical outcomes of a novel EDOF intraocular lens: a functional classification approachCONCLUSIONS: The 877PEY model demonstrated capability as a PRoF-Ex IOL with remarkable performance. It is safe to use and delivers a high degree of patient satisfaction.

Implantable Phakic Contact Lens: A Systematic ReviewCONCLUSION: The (diffractive) IPCL is a promising pIOL, with current published data showing overall good results. Interpretation of the monofocal IPCL is hampered by the suboptimal pre-operative CDVA leading to worse post-operative UDVA compared to the golden standard ICL. Direct comparative studies show similar results in both groups. Further research is needed to draw a…

Chatbots ability to produce leaflets on cataract surgeryNo abstract

Harnessing the Underutilized Potential of Lens Capsule Transplantation in Ophthalmology: A Narrative Review of Current Applications and Future DirectionsThe human lens capsule is a transparent and durable basement membrane routinely discarded during cataract surgery, exhibiting unique biochemical, biomechanical, and immunologic properties. This narrative review discusses validated ophthalmic applications across corneal, retinal, and glaucoma filtration surgeries. It emphasizes the capsule's emerging role as a tissue-engineering scaffold for cultivating corneal endothelial cells, limbal epithelial stem…

Child With Ruptured Soemmering Ring and Visual Axis ReopacificationNo abstract

A case report: iridociliary melanocytoma associated with secondary glaucomaCONCLUSIONS: This case underscores the importance of obtaining adequate tumor specimens for accurate diagnosis via FNAB in iris and ciliary body tumors. Additionally, for patients with secondary glaucoma, partial iridocyclectomy emerges as a promising intervention, addressing anterior chamber angle obstruction to alleviate IOP while facilitating histopathological diagnosis for subsequent management.

Surgical Outcomes of Retropupillary Iris-Claw Intraocular Lens Implantation for Various IndicationsCONCLUSIONS: RP-IOL implantation is an effective and safe option for secondary IOL implantation or exchange in cases of aphakia, IOL dislocation, and IOL opacification. The procedure offers significant improvements in visual acuity and a reduction in intraocular pressure, with manageable postoperative complications. While the study supports the use of RP-IOL as a viable option, further…

Corneal Endothelial Cell Loss in Shallow Anterior Chamber Eyes After Phacoemulsification Using the Eight-Chop TechniqueObjectives: In this study, the correlation between anterior chamber depth (ACD) and corneal endothelial cell density (CECD) loss was evaluated, and an assessment was made of the safety and efficacy of the eight-chop technique in cataract surgery for patients with shallow anterior chamber (SAC) depth. Methods: The technique was applied to patients with SAC and…

Comparison of Cost-Utility, Visual Acuity, and Humanistic Outcomes of Cataract Surgery Performed in the United States Versus International Outreach CampaignsBackground: This study compares the cost-utility, visual acuity, and humanistic outcomes of phacoemulsification surgery performed during international outreach campaigns to outcomes in the U.S. Objective: Humanitarian organizations frequently perform cataract surgeries in underserved regions, yet the outcomes of phacoemulsification in these settings remain unexplored. This study aims to compare the visual acuity outcomes, quality-of-life outcomes,…

Effect of Eyelid Opener on Wound Closure Time in Cataract SurgeryBackground: This study evaluates the effect of limiting eyelid opening on wound closure time and surgical outcomes during cataract surgery. Methods: This retrospective study included 129 patients who had undergone cataract surgery between December 2023 and March 2024. The patients were divided into two groups based on the degree of eyelid opening: full eyelid opening…

Does Ultrasound Energy Applied During Phacoemulsification Influence the Thickness of Intraretinal Layers?Background: Phacoemulsification (PE) is a gold standard method of cataract surgery. PE causes structural changes in the macula of the eye. The aim was to determine the amount of ultrasound (US) energy applied during PE, the change in thickness of the intraretinal layers, and the correlation between the applied US energy and the change in…

Burden of cataracts in developing countries: a trend analysis based on data from China, 1990 to 2021CONCLUSION: Despite advancements in cataract treatment that have alleviated some of the disease burden, population growth and aging continue to drive the increasing prevalence of cataract-related vision impairment in China. Addressing gender disparities and improving access to cataract surgery and preventive care are crucial for reducing this growing burden.

Bleb Complications after XEN Gel Stent implantation Linked to Mitomycin C (MMC)CONCLUSIONS AND IMPORTANCE: Xen Gel Stent implantation with mitomycin C was associated with scleral melt and blebitis, similar to reports following trabeculectomy. Adjunctive antimetabolite use should consider individualized patient risk profiles.

Factors Influencing Discrepancies in Intraocular Pressure Measurements Between iCare IC200 and Goldmann TonometerCONCLUSIONS: RBT tends to overestimate IOP relative to GAT in patients with thicker CCTs, while it underestimates IOP in those with higher GAT-measured IOP or a history of cataract surgery.

Evaluation of safety and stability after intraocular lens implantation using a novel material-crosslinked polyisobutylene: A preliminary studyCONCLUSIONS: The new xPIB IOL exhibited excellent in-the-bag stability and visual rehabilitation after cataract removal. Although the incidence was higher, the anterior capsule contraction in the xPIB group was not clinically significant and did not negatively impact vision.

Refraction Predictability for a Capsulotomy-Fixated Intraocular Lens in Femtosecond Laser-Assisted Cataract SurgeryCONCLUSIONS: Implantation of the capsulotomy-fixated FEMTIS IOL during FLACS is associated with increased systematic refractive PE, which is directly influenced by preoperative anterior chamber depth and lens thickness. IOL constant optimization enhances prediction accuracy. Relevant inaccuracies also persist in modern formulas, indicating that advancements beyond constant optimization might be crucial to enhance the predictability and…

Postoperative Visual Function of Enhanced Monofocal Intraocular Versus Monofocal LensesCONCLUSIONS: The Impress group demonstrated superior intermediate visual acuity and a myopic shift from the target refraction. Preoperative pupil diameter may help identify patients most likely to benefit from the Impress lens. [J Refract Surg. 2025;41(6):e551-e557.].

Recognition of early cognitive impairment in patients with cataractObjective: To explore the influencing factors of early cognitive impairment in patients with age-related cataract, and to construct a risk prediction model, for the management of patients undergoing day surgery. Methods: This was a cross-sectional study. A total of 137 patients with age-related cataract admitted to the Department of Ophthalmology, Chinese PLA General Hospital from…

The clinical efficacy of combining endoscopic cyclophotocoagulation (ECP) with cataract extraction in the therapeutic intervention for malignant glaucoma following trabeculectomyCONCLUSIONS: The combination of ECP and cataract extraction proves to be a safe and effective therapeutic approach for managing malignant glaucoma following anti-glaucoma surgery.

Optometry co-management of preoperative and postoperative cataract surgery patientsPURPOSE OF REVIEW: As the prevalence of cataracts continues to rise, the increasing demand for cataract surgery may surpass the availability of ophthalmologists. This review examines the role of optometry in the co-management of patients with cataracts, including preoperative and postoperative care, and discusses the implications of expanding optometric scope-of-practice laws.

Lens position change following cataract surgery in eyes with thick lenses: an SS-OCT based studyCONCLUSION: Postoperative forward IOL movement contributes to myopic PEs of eyes with thick lenses.

Reproducibility and accuracy of corneal curvature measurements in patients with and without dry eye: a device-based studyCONCLUSION: Dry eye significantly affects the reliability of corneal curvature measurements, especially with optical reflection-based devices. Corneal topography and Pentacam are more sensitive to tear film abnormalities, while the IOL Master 700 and OPD-Scan III show more consistent results, making them preferable for clinical practice, such as clinical applications including refractive surgery planning, contact lens…

Potential relationship between cataract surgery and ocular Demodex colonizationCONCLUSION: Our study revealed a significant increase in Demodex spp. prevalence at the first postoperative month in patients who underwent uncomplicated cataract surgery and who did not have preoperative dry eye syndrome or ocular surface disease. In light of our findings, ocular surface symptoms, such as stinging, burning, tearing, and itching, following cataract surgery should…

Surgical Outcomes of Gonioscopy-Assisted Transluminal Trabeculotomy (GATT) in Primary and Secondary Open- and Closed-Angle GlaucomaBackground: Gonioscopy-assisted transluminal trabeculotomy (GATT) is a minimally invasive, ab interno conjunctival-sparing glaucoma surgery aimed at the trabecular meshwork and the inner wall of Schlemm's canal. The goal of this study is to report on the success of GATT in a large group of patients with a wide variety of open- and closed-angle glaucomas with…

Affordable Sinskey Hook Goniotomy and Cataract Surgery in Black and Afro-Latino Patients Diagnosed with Glaucoma: Retrospective Real-World One-Year ResultsBackground/Objectives: This study aimed to evaluate the effectiveness of early phacoemulsification cataract surgery combined with goniotomy using a Sinskey hook in patients with glaucoma. Methods: This was a retrospective study conducted at Advanced Eye Care of New York; a private practice located in New York City. Most patients carried diagnoses of mild to moderate glaucoma…

Long-Term Clinical and Structural Outcomes Following Iris-Claw IOL Exchange for Dislocated Intraocular LensesObjectives: Intraocular lens dislocation is a well-recognized complication of cataract surgery, necessitating secondary interventions such as retropupillary iris-claw IOL implantation. While effective, this procedure requires larger incisions that may induce significant astigmatism. This study aimed to (1) evaluate anterior chamber changes following retropupillary ICIOL implantation and (2) compare surgically induced astigmatism between corneal and scleral…

Impact of Well-Controlled Type 2 Diabetes on Corneal Endothelium Following Cataract Surgery: A Prospective Longitudinal AnalysisBackground: The aim of this study was to evaluate corneal endothelial changes following phacoemulsification cataract surgery with intraocular lens implantation in patients with type 2 diabetes (study group) and without diabetes (control group). The study aimed to determine the extent of endothelial cell damage and the regenerative capacity of the cornea in patients with well-controlled…

Comparison of Conventional Keratometry and Total Keratometry in Untreated Myopic Eyes and Eyes After Keratorefractive Lenticule Extraction (KLEx)CONCLUSION: This study demonstrates that TK-values provide a more comprehensive assessment of corneal power, especially after KLEx, where changes in the posterior corneal surface become increasingly significant. The correlations suggest that patients with higher degrees of preexistent myopia or significant amount of laser ablation require special consideration in their refractive corneal assessments.

Corneal Endothelial Changes After Phacoemulsification Using the Eight-Chop Technique in Diabetic EyesBackground/Objectives: To analyze corneal endothelial changes and intraocular pressure (IOP) after phacoemulsification combined with the eight-chop technique and intraoperative parameters in patients with diabetes mellitus. Methods: The eyes of patients with cataracts who underwent phacoemulsification were analyzed in this study. Based on their hemoglobin A1c levels, patients were divided into two groups. The eight-chop technique…

Risk factors for error in refractive astigmatism after toric intraocular lens implantation in Chinese patientsCONCLUSIONS: Factors contributing to ERA after toric IOL implantation include age, AL and ACD change before and after the surgery.

Posterior optic capture for repositioning of dislocated three-piece intraocular lens: a single center retrospective studyCONCLUSIONS: POC is a minimally invasive and straightforward technique for intermediate-term fixation of dislocated three-piece IOLs.

A Questionnaire Study on Patient Perspectives of Sedation for Ophthalmic ProceduresIntroduction Ophthalmic procedures, such as cataract and refractive surgery, are prevalent in the United States and are often associated with significant preoperative anxiety among patients, which can impact patient comfort and surgical outcomes. Sedation is used in the vast majority of these procedures to reduce anxiety and improve patient cooperation. However, there is limited information…

Timing of the modified yamane technique in complicated cataract surgery: same session or second session?CONCLUSION: In cases of complicated cataract with loss of capsular support,the MYT,whether performed in the same session or in a second session, yielded comparable visual and refractive outcomes. While complications were more frequent in the early postoperative period in the group undergoing surgery in the same session,no complications were observed in either group during the…

Retrospective evaluation of changes in choroidal thickness after cataract surgeryIn this retrospective study, we investigated the changes in choroidal thickness (CT) using enhanced depth imaging spectral domain-optical coherence tomography (EDI-OCT) and intraocular pressure (IOP) following phacoemulsification. Twenty eyes of 18 patients who underwent phacoemulsification and intraocular lens implantation were included in this study. All patients underwent a detailed ophthalmologic examination. EDI-OCT was used to…

Cost analysis of immediate versus delayed bilateral cataract surgery in seniors in community-based ambulatory surgical centers in a post-COVID-19 eraCONCLUSIONS: The average costs of cataract extraction among senior patients in ambulatory surgical centers were significantly lower for ISBCS compared to DSBCS.

Comparison of 11 intraocular lens power calculation formulas in eyes undergoing simultaneous cataract surgery and Descemet membrane endothelial keratoplastyCONCLUSION: Prediction of the postoperative refraction in eyes requiring cataract surgery and DMEK is still challenging and not as accurate, as in healthy eyes without corneal abnormalities. In our case series, the Barrett Universal II formula achieved the overall best results. Although not being statistically significant, this outcome should be taken into account, when calculating…

Implantable Phakic Contact Lens: A Systematic ReviewCONCLUSION: The (diffractive) IPCL is a promising pIOL, with current published data showing overall good results. Interpretation of the monofocal IPCL is hampered by the suboptimal pre-operative CDVA leading to worse post-operative UDVA compared to the golden standard ICL. Direct comparative studies show similar results in both groups. Further research is needed to draw a…

Comparison of Cost-Utility, Visual Acuity, and Humanistic Outcomes of Cataract Surgery Performed in the United States Versus International Outreach CampaignsBackground: This study compares the cost-utility, visual acuity, and humanistic outcomes of phacoemulsification surgery performed during international outreach campaigns to outcomes in the U.S. Objective: Humanitarian organizations frequently perform cataract surgeries in underserved regions, yet the outcomes of phacoemulsification in these settings remain unexplored. This study aims to compare the visual acuity outcomes, quality-of-life outcomes,…

Surgical Outcomes of Retropupillary Iris-Claw Intraocular Lens Implantation for Various IndicationsCONCLUSIONS: RP-IOL implantation is an effective and safe option for secondary IOL implantation or exchange in cases of aphakia, IOL dislocation, and IOL opacification. The procedure offers significant improvements in visual acuity and a reduction in intraocular pressure, with manageable postoperative complications. While the study supports the use of RP-IOL as a viable option, further…

Pediatric cataract-part 2 : Surgical treatmentPediatric cataract surgery is very different from adult cataract surgery. A profound understanding of surgical technique, age at time of surgery, combined ocular and systemic diseases to be associated with long-term functional or morphological outcomes is important for planning and performing treatment of cataracts in children. Increased intra- and postoperative risk and individual amblyogenic risk…

Cataract in childhood-Part 1 : Diagnostics and preoperative managementCataract in childhood can be associated with a high amblyogenic risk depending on the age at onset, extent of lens opacity and cataract laterality and accompanying ocular diseases. Early diagnosis and initiation of adequate treatment of a cataract in childhood are essential for a favorable long-term development of visual acuity. The decision for or against…

Risk factors and incidence of Macular Edema in eyes with retinal Vein Occlusion after uneventful cataract surgery: The MEVO studyCONCLUSION: The study demonstrates that RVO eyes with previous CME requiring intravitreal treatment are at significant risk of postoperative macular edema after uneventful cataract surgery, and this risk increases in people with diabetes. The incidence is not affected by the type of RVO. Considering almost 2/3 rd of PME developed within the 1 st month…

Correlation of Blood Glucose Control With Cystoid Macular Edema and Central Macular Thickness After Cataract Surgery in DiabeticsCONCLUSION: Postoperative HbA1c levels have a strong correlation with CME and CMT thickening and may be reliable and valid biomarkers.

Potential association of bilateral macular edema with retinal vein occlusion triggered by volatile organic compounds of paint: A case reportCONCLUSIONS AND IMPORTANCE: A CME might be exacerbated by the exposure to paint-related VOCs. Our findings suggest that reducing and avoiding the occupational exposure to VOCs and regular measurements of urinary VOC concentration are important for those who work in the printing and painting industries.